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著作: Sinsuat Marodina/[財田 伸介]/[河田 佳樹]/[仁木 登]/Ohmatsu Hironobu/Tsuchida Takaaki/Kakinuma Ryutaro/Kusumoto Masahiko/Eguchi Kenji/Kaneko Masahiro/Moriyama Noriyuki/Influence of slice thickness on diagnoses of pulmonary nodules using low-dose CT: potential dependence of detection and diagnostic agreement on features and location of nodule/[Academic Radiology]

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EID
221769
EOID
658187
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LastModified
2012年9月5日(水) 11:53:56
Operator
大家 隆弘
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仁木 登
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種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨 Peer Review
カテゴリ 推奨
共著種別 推奨
学究種別 推奨
組織 推奨
  1. 徳島大学.工学部.光応用工学科
著者 必須
  1. (英) Sinsuat Marodina
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. 財田 伸介
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. 河田 佳樹([徳島大学.大学院社会産業理工学研究部.理工学域.光応用系.光情報システム分野]/[徳島大学.理工学部.理工学科.情報光システムコース.光情報システム講座])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. 仁木 登
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. (英) Ohmatsu Hironobu
    役割 任意
    貢献度 任意
    学籍番号 推奨
  6. (英) Tsuchida Takaaki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  7. (英) Kakinuma Ryutaro
    役割 任意
    貢献度 任意
    学籍番号 推奨
  8. (英) Kusumoto Masahiko
    役割 任意
    貢献度 任意
    学籍番号 推奨
  9. (英) Eguchi Kenji
    役割 任意
    貢献度 任意
    学籍番号 推奨
  10. (英) Kaneko Masahiro
    役割 任意
    貢献度 任意
    学籍番号 推奨
  11. (英) Moriyama Noriyuki
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Influence of slice thickness on diagnoses of pulmonary nodules using low-dose CT: potential dependence of detection and diagnostic agreement on features and location of nodule

副題 任意
要約 任意

(英) The aims of this study were to assess the influence of slice thickness on the ability of radiologists to detect or not detect nodules and to agree or disagree on the diagnosis and also to investigate the potential dependence of these relations on the sizes, average computed tomographic (CT) values, and locations of the nodules. Six radiologists performed qualitative diagnostic readings of multislice CT images with a slice thickness of 2 or 10 mm obtained from 360 subjects. The nodules were diagnosed as nodules for further examination (NFEs), inactive nodules for no further examination (INNFEs), or no abnormality. The results of the diagnoses were cross-tabulated and quantitatively analyzed using the average CT values, sizes, and locations of the nodules with reference to the 2-mm slices. Multivariate logistic regression analyses were used to estimate the significant associations of these parameters with the ability of radiologists to detect or not detect nodules and to agree or disagree on the diagnosis. Totals of 130 NFEs and 403 INNFEs for 2-mm slice thickness and 142 NFEs and 338 INNFEs for 10-mm slice thickness were diagnosed. Nodule classifications were as follows: the same diagnosis on both slice thickness images (67.6%), different diagnoses on two slice thickness images (21%), missed on 10-mm slice thickness images (10.6%), and misinterpreted on 10-mm slice thickness images (0.7%). Regarding detection and nondetection, NFE diagnoses were influenced by size (odds ratio [OR], 132.50; 95% confidence interval [CI], 4.77-4711) and the average CT value (OR, 27.20; 95% CI, 3.21-645.3), and INNFE diagnoses were influenced by size (OR, 16.10; 95% CI, 6.18-55.19) and the average CT value (OR, 7.67; 95% CI, 2.19-30.91). Regarding diagnostic agreement and disagreement, the NFE diagnoses were influenced by size (OR, 3.60; 95% CI, 1.29-11.04), nodule distance from the lung border (OR, 2.85; 95% CI, 1.27-6.65), and nodule location in the right upper lobe (OR, 0.07; 95% CI, 0.003-0.477), while the INNFE diagnoses were influenced by the average CT value (OR, 11.84; 95% CI, 3.33-55.86), size (OR, 0.42; 95% CI, 0.25-0.70), and nodule distance from the lung border (OR, 0.41; 95% CI, 0.25-0.66). The influence of slice thickness on the ability of radiologists to detect or not detect nodules and to agree or disagree on the diagnosis was quantitatively evaluated. Detection and nondetection of NFEs and INNFEs are influenced by size and average CT value. Agreement and disagreement on NFE and INNFE diagnoses are influenced not only by size and average CT value but also, importantly, by the locations of nodules.

キーワード 推奨
  1. (英) Adult
  2. (英) Aged
  3. (英) Algorithms
  4. (英) Cell Count
  5. (英) Diagnosis, Differential
  6. (英) Female
  7. (英) Humans
  8. (英) Lung Neoplasms
  9. (英) Male
  10. (英) Middle Aged
  11. (英) Multiple Pulmonary Nodules
  12. (英) Observer Variation
  13. (英) Radiation Dosage
  14. (英) Retrospective Studies
  15. (英) Tomography, X-Ray Computed
発行所 推奨
誌名 必須 Academic Radiology(Association of University Radiologists)
(pISSN: 1076-6332, eISSN: 1878-4046)
ISSN 任意 1878-4046
ISSN: 1076-6332 (pISSN: 1076-6332, eISSN: 1878-4046)
Title: Academic radiology
Title(ISO): Acad Radiol
Publisher: Elsevier USA
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 18
必須 5
必須 594 604
都市 任意
年月日 必須 2011年 5月 初日
URL 任意
DOI 任意 10.1016/j.acra.2011.01.007    (→Scopusで検索)
PMID 任意 21377905    (→Scopusで検索)
NAID 任意
WOS 任意
Scopus 任意
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.Affiliation: Functional Systems Engineering, University of Tokushima, Japan.

  2. (英) Article.PublicationTypeList.PublicationType: Journal Article