221739: Kitayama Atsushi/[有澤孝吉]/[上村浩一]/[日吉峰麗]/Takami Hidenobu/Sawachika Fusakazu/[山口美輪]/Nakamoto Mariko/Hasegawa Manabu/Tanto Masaharu/Shima Masayuki/Sumiyoshi Yoshio/Morinaga Kenji/Kodama Kazunori/Suzuki Taka-ichiro/Nagai Masaki/Satoh Hiroshi/Correlations of fish intake and plasma docosahexaenoic acid levels with each congener of PCDDs/PCDFs/dioxin-like PCBs in blood from the Japanese population/[International Archives of Occupational and Environmental Health]

著作: Kitayama Atsushi/[有澤孝吉]/[上村浩一]/[日吉峰麗]/Takami Hidenobu/Sawachika Fusakazu/[山口美輪]/Nakamoto Mariko/Hasegawa Manabu/Tanto Masaharu/Shima Masayuki/Sumiyoshi Yoshio/Morinaga Kenji/Kodama Kazunori/Suzuki Taka-ichiro/Nagai Masaki/Satoh Hiroshi/Correlations of fish intake and plasma docosahexaenoic acid levels with each congener of PCDDs/PCDFs/dioxin-like PCBs in blood from the Japanese population/[International Archives of Occupational and Environmental Health]

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EID: 221739
EOID: 852622
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LastModified: 2017年4月7日(金) 20:03:06
Operator: 有澤孝吉
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種別

必須

学術論文(審査論文)

言語

必須

英語

招待

推奨

審査

推奨

Peer Review

カテゴリ

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研究

共著種別

推奨

学究種別

推奨

博士課程学生による研究報告

組織

推奨

徳島大学.大学院ヘルスバイオサイエンス研究部.医療創生科学部門.社会環境衛生学講座.予防医学(2004年4月1日〜2015年3月31日)

著者

必須

(英) Kitayama Atsushi

役割任意

貢献度任意

学籍番号推奨
有澤孝吉([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.社会医学系.予防医学])

役割任意

貢献度任意

学籍番号推奨
上村浩一

役割任意

貢献度任意

学籍番号推奨
日吉峰麗

役割任意

貢献度任意

学籍番号推奨
(英) Takami Hidenobu

役割任意

貢献度任意

学籍番号推奨
(英) Sawachika Fusakazu

役割任意

貢献度任意

学籍番号推奨
山口美輪

役割任意

貢献度任意

学籍番号推奨
(英) Nakamoto Mariko

役割任意

貢献度任意

学籍番号推奨
(英) Hasegawa Manabu

役割任意

貢献度任意

学籍番号推奨
(英) Tanto Masaharu

役割任意

貢献度任意

学籍番号推奨
(英) Shima Masayuki

役割任意

貢献度任意

学籍番号推奨
(英) Sumiyoshi Yoshio

役割任意

貢献度任意

学籍番号推奨
(英) Morinaga Kenji

役割任意

貢献度任意

学籍番号推奨
(英) Kodama Kazunori

役割任意

貢献度任意

学籍番号推奨
(英) Suzuki Taka-ichiro

役割任意

貢献度任意

学籍番号推奨
(英) Nagai Masaki

役割任意

貢献度任意

学籍番号推奨
(英) Satoh Hiroshi

役割任意

貢献度任意

学籍番号推奨

題名

必須

(英) Correlations of fish intake and plasma docosahexaenoic acid levels with each congener of PCDDs/PCDFs/dioxin-like PCBs in blood from the Japanese population

副題

任意

要約

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(英) The purpose of the present study was to investigate the factors associated with blood levels of each congener of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (DL-PCBs) in the Japanese population. A cross-sectional study was performed on 1,656 subjects (755 men and 901 women) aged 15-73 years, who were living in 90 different areas of 30 prefectures in Japan. Blood levels of 29 PCDD, PCDF, and DL-PCB congeners were determined by high-resolution gas chromatography/mass spectrometry. In addition, a questionnaire survey on life style, including dietary habit, was carried out. The median total toxicity equivalent (TEQ) was 17 pgTEQ/g lipid. After adjustment for age, sex, body mass index, smoking habit, and consumption of other food groups, six PCDDs/PCDFs with 4-6 substituted chlorine atoms and 10 DL-PCBs, but not HeptaCDD/F or OctaCDD, showed significant positive correlations with the frequency of intake of fish and shellfish. Furthermore, significant positive relationships were also found between plasma levels of docosahexaenoic acid (DHA), a biomarker of fish intake, and 10 PCDDs/PCDFs with 4-6 chlorine atoms and 10 DL-PCBs. The partial correlation coefficients with plasma DHA were significantly higher for DL-PCBs than for PCDDs/PCDFs, and partial correlation coefficients for PCDDs/PCDFs significantly decreased with increasing number of chlorine atoms (Spearman r = -0.80, P = 0.001). Blood levels of PCDDs/PCDFs with 4-6 chlorine atoms and DL-PCBs were positively associated with fish intake in the Japanese population. These results may be explained by the higher degree of bioaccumulation of these congeners in fish and shellfish in the ecosystem, and the high consumption of fish among the Japanese population.

キーワード

推奨

(英) Adolescent
(英) Adult
(英) Aged
(英) Animals
(英) Benzofurans
(英) Cross-Sectional Studies
(英) Docosahexaenoic Acids
(英) Environmental Monitoring
(英) Female
(英) Fishes
(英) Food Contamination
(英) Food Habits
(英) Humans
日本(Japan)
(英) Male
(英) Middle Aged
(英) Polychlorinated Biphenyls
(英) Polymers
(英) Seafood
(英) Tetrachlorodibenzodioxin
(英) Water Pollutants, Chemical
(英) Young Adult

発行所

推奨

Springer

誌名

必須

International Archives of Occupational and Environmental Health([Springer-Verlag])

(pISSN: 0340-0131, eISSN: 1432-1246)

ISSN	任意	1432-1246 ISSN: 0340-0131 (pISSN: 0340-0131, eISSN: 1432-1246) Title: International archives of occupational and environmental health Title(ISO): Int Arch Occup Environ Health Supplier: Springer Online Journal Archive Publisher: Springer (NLM Catalog) (Scopus) (CrossRef) (Scopus information is found. [need login])

巻

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号

必須

頁

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927 951

都市

任意

年月日

必須

2011年 11月 17日

URL

任意

DOI

任意

10.1007/s00420-011-0618-7 (→Scopusで検索)

PMID

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21298441 (→Scopusで検索)

CRID

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WOS

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Scopus

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評価値

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被引用数

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指導教員

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備考

任意

(英) Article.Affiliation: Department of Preventive Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
(英) Article.PublicationTypeList.PublicationType: Journal Article

徳島大学教育・研究者情報データベース(EDB)

Education and Research Database (EDB), Tokushima University