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著作: Ikefuji Hiroyuki/[野村 昌弘]/[中屋 豊]/Mori Toshifumi/Kondo Noriyasu/Leishi Kiyoshi/Fujimoto Sayuri/[伊東 進]/Visualization of cardiac dipole using a current density map: detection of cardiac current undetectable by electrocardiography using magnetocardiography./[The Journal of Medical Investigation : JMI]

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EID
162893
EOID
907281
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0
LastModified
2018年5月23日(水) 17:08:29
Operator
[ADMIN]
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Owner
[学科長]/[徳島大学.医学部.医科栄養学科]
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種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨 Peer Review
カテゴリ 推奨 研究
共著種別 推奨
学究種別 推奨
組織 推奨
  1. 徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.医療栄養科学講座(2004年4月1日〜)
著者 必須
  1. (英) Ikefuji Hiroyuki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. 野村 昌弘
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. 中屋 豊
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. (英) Mori Toshifumi
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. (英) Kondo Noriyasu
    役割 任意
    貢献度 任意
    学籍番号 推奨
  6. (英) Leishi Kiyoshi
    役割 任意
    貢献度 任意
    学籍番号 推奨
  7. (英) Fujimoto Sayuri
    役割 任意
    貢献度 任意
    学籍番号 推奨
  8. 伊東 進
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Visualization of cardiac dipole using a current density map: detection of cardiac current undetectable by electrocardiography using magnetocardiography.

副題 任意
要約 任意

(英) A close relationship exists between electric current and the magnetic field. However, electricity and magnetism have different physical characteristics, and magnetocardiography (MCG) may provide information on cardiac current that is difficult to obtain by electrocardiography (ECG). In the present study, we investigated the issue of whether the current density map method, in which cardiac current is estimated from the magnetic gradient, facilitates the visualization of cardiac current undetectable by ECG. The subjects were 50 healthy adults (N group), 40 patients with left ventricular overloading (LVO group), 15 patients with right ventricular overloading (RVO group), 10 patients with an old inferior myocardial infarction (OMI group), and 30 patients with diabetes mellitus (DM group). MCGs were recorded with a second derivative superconducting quantum interference device (SQUID) gradiometer using liquid helium. Isopotential maps and current density maps from unipolar precordial ECG leads and MCGs, respectively, were prepared, and the cardiac electric current was examined. The current density map at the ventricular depolarization phase showed one peak of current density in the N group. However, in the OMI group, the current density map showed multiple peaks of current density areas. In the RVO group, two peaks of current densities were detected at the right superior region and left thoracic region and these two diploles appeared to be from the right and left ventricular derived cardiac currents, respectively. Moreover, there was a significant correlation between the magnitude of the current density from the right ventricle and the systolic pulmonary arterial pressure. The current density map at the ventricular repolarization phase in the N group showed only a single current source. However, abnormal current sources in the current density maps were frequently detected even in patients showing no abnormalities on isopotential maps in the LVO, DM, and OMI groups. The findings herein suggest that opposing dipoles of the ventricular depolarization and repolarization vectors were summed and evaluated as a single dipole in the electrocardiogram. However, MCG facilitated the detection of multiple dipoles because of its superior spatial resolution as well as difference in physical properties between magnetic and electrical fields. Our results suggest that MCG with a current density map is useful for detecting cardiac current undetectable by ECG in an early stage.

キーワード 推奨
  1. (英) Adult
  2. (英) Aged
  3. 糖尿病(diabetes mellitus)
  4. (英) Electrocardiography
  5. (英) Female
  6. 心臓(heart)
  7. (英) Humans
  8. (英) Magnetocardiography
  9. (英) Male
  10. (英) Middle Aged
  11. (英) Myocardial Infarction
  12. (英) Ventricular Dysfunction, Left
発行所 推奨
誌名 必須 The Journal of Medical Investigation : JMI([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
ISSN 任意 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 54
必須 1-2
必須 116 123
都市 任意
年月日 必須 2007年 2月 初日
URL 任意
DOI 任意 10.2152/jmi.54.116    (→Scopusで検索)
PMID 任意 17380022    (→Scopusで検索)
NAID 任意
WOS 任意
Scopus 任意 2-s2.0-34247869051
機関リポジトリ 111502
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.Affiliation: Department of Cardiology, JA Kochi Hospital, Kochi, Japan.

  2. (英) Article.PublicationTypeList.PublicationType: Journal Article