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著作: [久保 真一]/[石上 安希子]/[後藤田 貴子]/[徳永 逸夫]/[北村 修]/An autopsy case of adrenal insufficiency 20 years after hypophysectomy: relation between stress and cause of death/[The Journal of Medical Investigation : JMI]

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EID
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878474
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2017年12月4日(月) 14:07:54
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石上 安希子
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種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨 Peer Review
カテゴリ 推奨
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学究種別 推奨
組織 推奨
  1. 徳島大学.大学院ヘルスバイオサイエンス研究部.再生修復医歯学部門.感覚運動系病態医学講座(2004年4月1日〜)
著者 必須
  1. 久保 真一
    役割 任意 共著
    貢献度 任意
    学籍番号 推奨
  2. 石上 安希子
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. 後藤田 貴子
    役割 任意 共著
    貢献度 任意
    学籍番号 推奨
  4. 徳永 逸夫
    役割 任意 共著
    貢献度 任意
    学籍番号 推奨
  5. 北村 修
    役割 任意 共著
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) An autopsy case of adrenal insufficiency 20 years after hypophysectomy: relation between stress and cause of death

副題 任意
要約 任意

(英) A 63-years-old man was found dead with the body soaking in water lying face up on a riverbank. Autopsy and diatom examination demonstrated that the cause of death was drowning. He had undergone hypophysectomy 20 years earlier. Autopsy, pathological and endocrinological findings demonstrated secondary and chronic hypothyroidism, hypogonadism, and adrenal insufficiency. The cadaver had fallen into the river, and received numerous wounds such as abrasions and subcutaneous hemorrhage. Moreover, it was suspected that he had developed hypothermia before death. Cortisol in the blood and 17- OHCS in urine were within the reference range. We suspect that the adrenocortical hormone was secreted into the blood as a result of various stresses due to wounds and hypothermia. However, it was suspected that sufficient hormone might not be secreted due to chronic adrenal insufficiency. This insufficient cortisol causes the decrease in the stress resistance, and might influence his cause of death. Moreover, as hypothyroidism decreases thermogenesis, he might have fallen into hypothermia easily. In addition, because both adrenocortical insufficiency and hypothyroidism caused the hypoglycemia, he might have fallen into the loss of consciousness. Therefore, it was considered that he had died by drowning, in relation to the adrenocortical insufficiency and panhypopituitarism.

キーワード 推奨
  1. (英) Adrenal Insufficiency
  2. (英) Autopsy
  3. (英) Cause of Death
  4. (英) Humans
  5. (英) Hypophysectomy
  6. (英) Hypopituitarism
  7. (英) Male
  8. (英) Middle Aged
  9. (英) Stress, Physiological
  10. (英) Time Factors
発行所 推奨
誌名 必須 The Journal of Medical Investigation : JMI([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
ISSN 任意 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 53
必須 1-2
必須 183 187
都市 任意
年月日 必須 2006年 2月 末日
URL 任意
DOI 任意 10.2152/jmi.53.183    (→Scopusで検索)
PMID 任意 16538014    (→Scopusで検索)
NAID 任意 110004749838
WOS 任意
Scopus 任意
機関リポジトリ 110806
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.Affiliation: Department of Forensic Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan.

  2. (英) Article.PublicationTypeList.PublicationType: Case Reports

  3. (英) Article.PublicationTypeList.PublicationType: Journal Article

  4. (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't