徳島大学 教育・研究者情報データベース(EDB)

1. (英) Furutani Kaori

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2. 原田 雅史([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.放射線医学])

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3. (英) Minato Masako

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4. 森田 奈緒美

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5. 西谷 弘

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(英) Regional changes of fractional anisotropy with normal aging using statistical parametric mapping (SPM).

(英) There has been reports on the usefulness of diffusion tensor imaging (DTI) about age-or disease-related degradation. DTI is generally evaluated by the region of interest (ROI) methodology. In this study, we applied a statistical way using Statistical Parametric Mapping (SPM) to assess normal aging by DTI and compared results of these two methods. Ten young and ten senior normal volunteers were examined. On SPM, tensor images were changed into normalized tensor images. They were compared between the two groups by t-test. In the senior group, fractional anisotropy (FA) values were higher on the basal ganglia, cingulated gyrus and other cortical gray matter, lower in the corona radiata, internal capsule, centrum semiovale and corpus callosum by using SPM. In the ROI method, the results were almost compatible except in the brain periphery. Aging changes on water diffusion anisotropy was clearly shown by SPM method which would be useful to evaluate change of water diffusion anisotropy without operator bias even in clinical setting instead of ROI measurement.

1. (英) Adult
2. (英) Aged
3. 加齢(aging/->キーワード[老化])
4. 異方性(anisotropy)
5. (英) Biometry
6. 脳(brain)
7. (英) Brain Mapping
8. (英) Female
9. (英) Humans
10. 磁気共鳴映像法(magnetic resonance imaging)
11. (英) Male
12. (英) Middle Aged

1. (英) Article.Affiliation: Department of Radiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.

2. (英) Article.PublicationTypeList.PublicationType: Journal Article