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著作: [宇野 昌明]/Ueda Shin/Hondo Hideki/Matsumoto Keizo/Harada Masahumi/Effectiveness of revascularization surgery evaluated by proton magnetic resonance spectroscopy and single photon emission computed tomography/[Neurologia Medico-Chirurgica]

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EID
136357
EOID
689222
Map
0
LastModified
2013年6月3日(月) 15:45:16
Operator
大家 隆弘
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Owner
[学科長]/[徳島大学.医学部.医学科]
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種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨
カテゴリ 推奨
共著種別 推奨
学究種別 推奨
組織 推奨
著者 必須
  1. 宇野 昌明
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. (英) Ueda Shin
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. (英) Hondo Hideki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. (英) Matsumoto Keizo
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. (英) Harada Masahumi
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Effectiveness of revascularization surgery evaluated by proton magnetic resonance spectroscopy and single photon emission computed tomography
副題 任意
要約 任意

(英) Proton magnetic resonance spectroscopy (MRS) and single photon emission computed tomography (SPECT) were used to evaluate chronic ischemic regions in 26 stroke patients before and 1, 3, and 6 months after revascularization surgery. The volume of interest for proton MRS was placed in an area including part of the frontal and temporal opercula, insular cortex, and basal ganglia. Twenty healthy volunteers served as controls for proton MRS. Patients were divided into three groups according to the preoperative proton MRS. Group A (n = 12) had significantly lower N-acetylaspartate/choline (NAA/Cho) and N-acetylaspartate/creatine (NAA/Cr) ratios on the operative side compared to those on the contralateral side, and also lower than those in normal subjects. In seven patients in Group A, postoperative serial proton MRS demonstrated no recovery of these ratios on the operative side. However, proton MRS of the other five patients indicated gradual improvement in these ratios on the operative side at 3 to 6 months after surgery, and SPECT indicated an increase in cerebral blood flow on the operative side in four of these five patients. In Group B (n = 9), proton MRS and SPECT showed no laterality before revascularization and no remarkable change during the postoperative course. In Group C (n = 5), NAA/Cho or NAA/Cr decreased on the contralateral side preoperatively. Two patients showed fluctuating values of NAA/Cho or NAA/Cr during the postoperative period. Serial proton MRS and SPECT studies may be useful for the evaluation of revascularization surgery on ischemic regions. The efficacy of revascularization surgery on the metabolism may appear gradually within 3-6 months.
キーワード 推奨
  1. (英) cerebral infarction
  2. 代謝(metabolism)
  3. 分光学(spectroscopy)
  4. 磁気共鳴映像法(magnetic resonance imaging)
  5. 脳血流量(cerebral blood flow)
発行所 推奨 (日) 日本脳神経外科学会 / (読) にほんのうしんけいげかがっかい
誌名 必須 Neurologia Medico-Chirurgica(日本脳神経外科学会)
(pISSN: 0470-8105, eISSN: 1349-8029)
ISSN 任意 0470-8105
ISSN: 0470-8105 (pISSN: 0470-8105, eISSN: 1349-8029)
Title: Neurologia medico-chirurgica
Title(ISO): Neurol Med Chir (Tokyo)
Supplier: 社団法人日本脳神経外科学会
Publisher: Japan Neurosurgical Society
 (NLM Catalog)   (Webcat Plus)   (Webcat Plus)   (Webcat Plus)   (医中誌Web)   (J-STAGE)   (Scopus)   (CrossRef)  (Scopus information is found. [need login])
巻 必須 36
号 必須 8
頁 必須 560 567
都市 任意
年月日 必須 1996年 8月 初日
URL 任意
DOI 任意 10.2176/nmc.36.560    (→Scopusで検索)
PMID 任意 8831198    (→Scopusで検索)
CRID 任意
WOS 任意
Scopus 任意
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意

  1. (英) Article.Affiliation: Department of Neurological Surgery, School of Medicine, University of Tokushima.

  2. (英) Article.PublicationTypeList.PublicationType: Comparative Study

  3. (英) Article.PublicationTypeList.PublicationType: Journal Article