徳島大学 教育・研究者情報データベース(EDB)

1. 有澤 孝吉

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2. 日吉 峰麗

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3. 武田 英雄([徳島大学.大学院医歯薬学研究部.医学域.総合研究支援センター])

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(英) Risk assessment of environmental factors and contribution to disease prevention

(日) 環境要因の健康リスク評価と疾病予防への貢献

(日) The research interest of authors has focused on the risk assessment of environmental pollutantssuch as cadmium and dioxin-related compounds, and epidemiology of human T-cell lymphotropicvirus type-I(HTLV-I)infection. The authors(1)showed that low-molecular weight proteinuriaand reduced glomerular filtration rate caused by environmental cadmium were strongly associatedwith shortened survival，(2)clarified serological risk factors for development of adult T-cellleukemia/lymphoma among asymptomatic HTLV-I carriers(plasma levels of soluble interleukin2-receptor>＝500U/ml and HTLV-I antibody titer>＝1，024)，(3)conducted the first prospectivestudy of HTLV-I infection and development of malignances other than ATL, and found a significantlyreduced risk of gastric cancer among HTLV-I carriers, and(4)by a cooperative study, clarified anew pathogenicity of HTLV-I(association with Sj¨ogren's syndrome)

1. (英) cadmium
2. (英) dioxins
3. (英) human T-cell lymphotropic virus type-1
4. (英) risk assessment
5. (英) epidemiology